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7-8 oct. 2025 Nantes (France)
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Program > Speakers
Invited speakers:
• Berta Cillero-Pastor (Spatial Omics for Regenerative Medicine, Maastricht, NL)
Presentation title: From single cells to patient stratification: mass spectrometry-based omics approaches
Dr. Cillero-Pastor studied molecular biology and biochemistry at the Autonomous University of Madrid, Spain. She obtained her PhD at the INIBIC Institute of La Coruña (cum laude) after having been awarded a fellowship from the Carlos III Health Institute (Spain) to study the effect of pro-inflammatory cytokines in diseased cartilage. After having obtained an Angeles Alvariño fellowship, she then moved to Amsterdam to work as postdoctoral researcher at AMOLF. In this period, she developed new mass spectrometry imaging approaches in the field of orthopaedics. In 2015 she joined Maastricht University as CORE lab leader at the division of Imaging Mass Spectrometry (M4i). Since then, she has established her own research line on the application of mass spectrometry imaging and proteomics for different biomedical applications with special focus on cardiovascular research and musculoskeletal diseases. She has received funding from NWO and Horizon 2020, including several ITN grants.
• Judith Sluimer, Cardiovascular research institute, Maastricht University, Maastricht, Netherlands
Presentation title: Fibroblast identity, function and paracrine communication in vascular pathology
Prof. Dr. Judith Sluimer (Rotterdam, The Netherlands) earned her PhD from Maastricht University in 2008, investigating hypoxia in atherosclerosis under Prof. Mat Daemen's guidance. She then joined Prof. Ira Tabas's lab at Columbia University as a post-doc, delving into macrophage apoptosis and autophagy, funded by organizations like the Netherlands Scientific Organisation (NWO) and the International Atherosclerosis Society (IAS).
She established her independent research line in 2010, securing the NWO Veni grant and a tenure track at Maastricht UMC+. Judith and her team aim to reverse vascular aging and atherosclerotic plaque destabilization by understanding inflammatory and fibrotic cellular mechanisms. She combines experimental in vivo and in vitro models with single cell sequencing, studies involving human tissue samples, and non-invasive imaging. Her group's diverse collaborations have yielded significant insights into vascular cell heterogeneity and intercellular communication, supported by grants and fellowships from organizations like a Dutch Heart foundation personal fellowship, NWO VIDI, Marie Curie and a Humboldt fellowship. She actively engages in global research collaborations, contributing to projects like the Leducq grant scheme and affiliations with University of Edinburgh and RWTH Aachen.
In addition to research, teaching and mentoring, Judith has organized major scientific events and holds key roles in academic societies, previously serving as treasurer for the European Vascular Biology Organization, and contributing to ESC’s basic research council, and editorial boards of Cardiovascular Research and Vascular Pharmacology.
• Mirjana Efremova (Barts Cancer Institute, London, UK)
• Nicolas Chevrier (University of Chicago, USA)
• Yad Ghavi- Helm (Institut de Génomique Fonctionnelle de Lyon, Lyon)
Title of the talk: From single-cell to spatial transcriptomics
Biosketch: I obtained my PhD in 2009 from the University of Paris XI (France) working on transcription regulation in the yeast Saccharomyces cerevisiae in the team of Michel Werner at the CEA-Saclay. I then did a postdoc (and was later staff scientist) at the EMBL in Heidelberg (Germany), working on enhancer-promoter communication in Drosophila melanogaster in the team of Eileen Furlong. I returned to France in 2017 after obtaining a permanent CNRS position, and started my own team at the Fonctional Genomics Institute of Lyon (IGFL) at the ENS of Lyon (France). I obtained prestigious grants such as the ERC Starting grant. Since 2021, I co-lead the Spatial-Cell-ID spatial transcriptomic facility at the ENS of Lyon, which was funded thanks to a large grant from the French "investissement d'avenir" programme. I was promoted to Research Director at the CNRS in 2025.
The primary scientific interest of my team is to understand how gene expression is regulated during development. We particularly focus on the role of 3D genomic organization in this regulation. We combine this scientific goal with the development of experimental and bioinformatics spatial OMICs tools (within the frame of the Spatial-Cell-ID facility) applied to our scientific questions.
• Polina Arsenteva (Laboratory of Biology and Modeling of the Cell, ENS Lyon)
Presentation title: Intracranial Aneurysms: Insights from Single-Cell Profiling of Cerebral Arteries
Polina is a post-doctoral researcher at Jean Leray Mathematics Laboratory (Nantes Université). Polina did her Ph.D. at the Burgundy Institute of Mathematics (Université de Bourgogne). Her work in collaboration with the IRSN under the supervision of Hervé Cardot and Mohamed Amine Benadjaoud focused on modeling of adverse effects induced by radiotherapy on healthy tissues.
Her research interests now lie in the domain of mathematical modeling in the biomedical context. Her current position as a post-doc with ENS de Lyon in collaboration with Bertrand Michel and Franck Picard focuses on kernel-based machine learning for single cell data.
Local speakers:
• Anne-Clémence Vion (Institut du Thorax)
Presentation title: Intracranial Aneurysms: Insights from Single-Cell Profiling of Cerebral Arteries
During her initial studies in biological engineering, Anne-Clemence developed a curiosity for fundamental research and decided to pursue her training with a doctoral thesis. She therefore turned to vascular biology, a discipline at the interface between pure biology and fluid mechanics.
Since her recruitment as a researcher and the establishment of her own research group, she has followed two mutually complementary lines of research: i) studying the effect of mechanical forces on vascular cells and its possible contribution to intracranial aneurysm formation, ii) understanding the pathophysiological effect of rare variants associated with intracranial aneurysms (with Dr Loirand).
• Antoine Roquilly (CR2TI)
• Franck Halary (CR2TI)
• Jérémie Poschmann (CR2TI)
• Marie-Astrid Boutet (RMeS)
• Vincent Guen (CRCI²NA)
